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DeCS
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Descriptor English:
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ATP Binding Cassette Transporter, Subfamily G, Member 2
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Descriptor Spanish:
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Transportador de Casetes de Unión a ATP, Subfamilia G, Miembro 2
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Descriptor Portuguese:
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Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP
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Synonyms English:
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ABCG2 Protein
ABCG2 Transporter
ATP Binding Cassette Transporter, Sub-Family G, Member 2
CD338 Antigen
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Tree Number:
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D12.776.157.530.100.228.500
D12.776.395.550.020.457.500
D12.776.543.550.192.457.500
D12.776.543.585.100.228.500
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Definition English:
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ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS. |
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History Note English:
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2019 (2017)
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Allowable Qualifiers English:
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Record Number:
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56579
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Unique Identifier:
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D000070997
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Occurrence in VHL:
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Similar:
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DeCS
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