Search on: MFN=56577 
Descriptors Found: 1
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Descriptor English:   ATP Binding Cassette Transporter, Subfamily G 
Descriptor Spanish:   Transportador de Casetes de Unión a ATP, Subfamilia G 
Descriptor Portuguese:   Subfamília G de Transportadores de Cassetes de Ligação de ATP 
Synonyms English:   ABCG Proteins
ABCG Transporters
ATP Binding Cassette Transporter, Sub Family G
ATP Binding Cassette Transporter, Sub-Family G  
Tree Number:   D12.776.157.530.100.228
D12.776.395.550.020.457
D12.776.543.550.192.457
D12.776.543.585.100.228
Definition English:   A subfamily of ATP binding cassette transporters that function primarily in the transport of lipids and STEROLS across the CELL MEMBRANE. They also export UREA and various drugs resulting in MULTIDRUG RESISTANCE. They are smaller than most other ATP binding cassette proteins, consisting of six transmembrane alpha helices and a distinct N-terminal cytoplasmic ATP-binding domain, and function as homo- or heterodimers with other ABCG transporters. 
History Note English:   2019 (2017) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56577 
Unique Identifier:   D000070996 

Occurrence in VHL:
 

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