Search on: NUCLEOLYSIN 
Descriptors Found: 1
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Descriptor English:   Microbial Collagenase 
Descriptor Spanish:   Colagenasa Microbiana 
Descriptor Portuguese:   Colagenase Microbiana 
Synonyms English:   Clostridiopeptidase A
Clostridium histolyticum Collagenase
Clostridium histolyticum, Collagenase
Collagenase Clostridium histolyticum
Collagenase Like Peptidase
Collagenase, Clostridium histolyticum
Collagenase, Microbial
Collagenase-Like Peptidase
Collalysine
Nucleolysin
Peptidase, Collagenase-Like
histolyticum, Collagenase Clostridium  
Tree Number:   D08.811.277.656.300.480.205.500
D08.811.277.656.675.374.205.500
Definition English:   A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3. 
History Note English:   94; was CLOSTRIDIUM HISTOLYTICUM COLLAGENASE 1991-93; was CLOSTRIDIOPEPTIDASE A 1963-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   31813 
Unique Identifier:   D003012 

Occurrence in VHL:
 

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DeCS