Search on: NEUROPROTECTANTS 
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Descriptor English:   Neuroprotective Agents 
Descriptor Spanish:   Fármacos Neuroprotectores 
Descriptor Portuguese:   Fármacos Neuroprotetores 
Synonyms English:   Agents, Neuroprotective
Drugs, Neuroprotective
Effect, Neuroprotective
Effects, Neuroprotective
Neuroprotectants
Neuroprotective Drugs
Neuroprotective Effect
Neuroprotective Effects  
Tree Number:   D27.505.696.706.548
D27.505.954.427.575
Definition English:   Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids. 
Indexing Annotation English:   note entry term NEUROPROTECTIVE EFFECT: use only for the neuroprotective effect of a chemical substance
History Note English:   95 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   32116 
Unique Identifier:   D018696 

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