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NATALIZUMAB
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DeCS
Descriptor
English
:
Natalizumab
Descriptor
Spanish
:
Natalizumab
Descriptor
Portuguese
:
Natalizumab
Synonyms
English
:
Antegren
Tysabri
Tree Number:
D12.776.124.486.485.114.224.060.813
D12.776.124.790.651.114.224.060.813
D12.776.377.715.548.114.224.200.813
Definition
English
:
A humanized monoclonal immunoglobulin G4 antibody to human
INTEGRIN ALPHA4
that binds to the alpha4 subunit of
INTEGRIN ALPHA4BETA1
and integrin alpha4beta7. It is used as an IMMUNOLOGIC FACTOR in the treatment of RELAPSING-REMITTING
MULTIPLE SCLEROSIS
and CROHN'S
DISEASE.
Pharmacological Action:
Immunologic Factors
See Related
English
:
Integrin alpha4
History Note
English
:
2016 (2002)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55977
Unique Identifier:
D000069442
Occurrence in VHL
:
Similar:
DeCS