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MITOMYCIN
Descriptors Found:
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DeCS
Descriptor
English
:
Mitomycin
Descriptor
Spanish
:
Mitomicina
Descriptor
Portuguese
:
Mitomicina
Synonyms
English
:
Ametycine
Mitocin C
Mitocin-C
MitocinC
Mitomycin C
Mitomycin-C
Mutamycin
NSC 26980
NSC-26980
NSC26980
Tree Number:
D02.806.400.249.350
D03.383.097.500.350
D03.633.100.473.412.249.350
Definition
English
:
An antineoplastic antibiotic produced by
Streptomyces
caespitosus. It is one of the bi- or tri-functional
ALKYLATING AGENTS
causing cross-linking of DNA and inhibition of DNA synthesis.
Indexing Annotation
English
:
MITOMYCINS
is also available
Pharmacological Action:
Alkylating Agents
Antibiotics, Antineoplastic
Cross-Linking Reagents
Nucleic Acid Synthesis Inhibitors
Entry Combination - descr/qualif
English
:
Mitomycin
/
analogs & derivatives
use
Mitomycins
History Note
English
:
2000(1992); for MITOMYCIN use MITOMYCIN (NM) 1981-1991
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
29961
Unique Identifier:
D016685
Occurrence in VHL
:
Similar:
DeCS