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IL33
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DeCS
Descriptor
English
:
Interleukin-33
Descriptor
Spanish
:
Interleucina-33
Descriptor
Portuguese
:
Interleucina-33
Synonyms
English
:
IL-33
IL33
Interleukin 33
Tree Number:
D12.644.276.374.465.850
D12.776.467.374.465.850
D23.529.374.465.850
Definition
English
:
A member of the
INTERLEUKIN-1
protein
family
involved in the maturation of
TH2 CELLS
and the activation of
MAST CELLS
;
BASOPHILS
;
EOSINOPHILS
and NK CELLS. It is also produced by
ENDOTHELIAL CELLS
;
EPITHELIAL CELLS
and
FIBROBLASTS
; where it can function as an alarmin to modulate immune and inflammatory responses to
tissue
damage.
History Note
English
:
2016 (2005)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55965
Unique Identifier:
D000067596
Occurrence in VHL
:
Similar:
DeCS