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ICL-670
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DeCS
Descriptor
English
:
Deferasirox
Descriptor
Spanish
:
Deferasirox
Descriptor
Portuguese
:
Deferasirox
Synonyms
English
:
4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid
Exjade
ICL 670
ICL 670A
ICL-670
ICL-670A
ICL670
ICL670A
Tree Number:
D02.241.223.100.250
D02.455.426.559.389.127.266
D03.383.129.799.363
Definition
English
:
A triazole and benzoate derivative that acts as a selective iron chelator. It is used in the management of chronic
IRON OVERLOAD
due to
blood transfusion
or non-transfusion dependent
THALASSEMIA.
Pharmacological Action:
Iron Chelating Agents
History Note
English
:
2019 (2000)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57695
Unique Identifier:
D000077588
Occurrence in VHL
:
Similar:
DeCS