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P70S6K
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DeCS
Descriptor
English
:
Ribosomal Protein S6 Kinases, 70-kDa
Descriptor
Spanish
:
Proteínas Quinasas S6 Ribosómicas 70-kDa
Descriptor
Portuguese
:
Proteínas Quinases S6 Ribossômicas 70-kDa
Synonyms
English
:
Ribosomal Protein S6 Kinases, 70 kDa
S6 Kinase, p70
p70 S6 Kinase
p70s6k
Tree Number:
D08.811.913.696.620.682.700.862.249
D12.644.360.600.249
D12.776.476.600.249
Definition
English
:
A
family
of
ribosomal protein S6 kinases
that are considered the major physiological kinases for
RIBOSOMAL PROTEIN S6
. Unlike
RIBOSOMAL PROTEIN S6 KINASES
, 90KDa the
proteins
in this
family
are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa
proteins
, however
ALTERNATIVE SPLICING
of mRNAs for
proteins
in this class also results in 85kDa variants being formed.
History Note
English
:
2005(2003); for P70 S6 KINASE & P70S6K use RIBOSOMAL PROTEIN S6 KINASES 1998-2002
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
37341
Unique Identifier:
D038762
Occurrence in VHL
:
Similar:
DeCS