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O,P-DDD
Descriptors Found:
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DeCS
Descriptor
English
:
Mitotane
Descriptor
Spanish
:
Mitotano
Descriptor
Portuguese
:
Mitotano
Synonyms
English
:
Chloditan
Chlodithane
Khloditan
Lysodren
Mytotan
o,p-DDD
ortho,para DDD
ortho,para-DDD
Tree Number:
D02.455.526.439.681
Definition
English
:
A derivative of the insecticide
DICHLORODIPHENYLDICHLOROETHANE
that specifically inhibits cells of the
adrenal cortex
and their production of
hormones
. It is used to treat adrenocortical tumors and causes CNS damage, but no
bone marrow
depression.
Pharmacological Action:
Antineoplastic Agents, Hormonal
History Note
English
:
73
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
9129
Unique Identifier:
D008939
Occurrence in VHL
:
Similar:
DeCS