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DeCS
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Descriptor English:
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Zinc Finger E-box Binding Homeobox 2
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Descriptor Spanish:
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Caja Homeótica 2 de Unión a E-Box con Dedos de Zinc
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Descriptor Portuguese:
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Homeobox 2 de Ligação a E-box com Dedos de Zinco
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Synonyms English:
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Smad Interacting Protein 1
Smad-Interacting Protein 1
Transcription Factor, Zeb2
Zeb2 Transcription Factor
Zinc Finger E box Binding Homeobox 2
Zinc Finger E box Binding Homeobox 2 Protein
Zinc Finger E-box Binding Homeobox 2 Protein
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Tree Number:
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D12.776.260.400.883
D12.776.260.703.700
D12.776.930.780.918
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Definition English:
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A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME. |
History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57113
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Unique Identifier:
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D000074165
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Occurrence in VHL:
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Similar:
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DeCS
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