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RIBONUCLEASE H, HUMAN IMMUNODEFICIENCY VIRUS
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DeCS
Descriptor
English
:
Ribonuclease H, Human Immunodeficiency Virus
Descriptor
Spanish
:
Ribonucleasa H del Virus de la Inmunodeficiencia Humana
Descriptor
Portuguese
:
Ribonuclease H do Vírus da Imunodeficiência Humana
Synonyms
English
:
HIV RNAse H
HIV Ribonuclease H
RNAse H, HIV
Ribonuclease H, HIV
Tree Number:
D08.811.277.352.355.350.700.500
D08.811.277.352.700.350.700.500
D12.776.964.775.375.545.875.500
D12.776.964.775.562.764.875.500
D12.776.964.970.600.850.375.545.875.500
D12.776.964.970.600.850.375.750.187.500
Definition
English
:
A ribonuclease activity that is a component of the
HIV REVERSE TRANSCRIPTASE
. It removes the RNA strand of the RNA-DNA heteroduplex produced by
reverse transcription
. Once the RNA moiety is removed a double stranded DNA copy of the HIV RNA can be synthesized.
History Note
English
:
2008
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52675
Unique Identifier:
D054309
Occurrence in VHL
:
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DeCS