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PHENACETIN O-DEALKYLASE
Descriptors Found:
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DeCS
Descriptor
English
:
Cytochrome P-450 CYP1A2
Descriptor
Spanish
:
Citocromo P-450 CYP1A2
Descriptor
Portuguese
:
Citocromo P-450 CYP1A2
Synonyms
English
:
CYP 1A2
CYP1A2
CYP1A2, Cytochrome P-450
Caffeine Demethylase
Cytochrome P 450 CYP1A2
Cytochrome P 450 LM4
Cytochrome P 450d
Cytochrome P-450 LM(4)
Cytochrome P-450 LM4
Cytochrome P-450d
Cytochrome P450 1A2
Demethylase, Caffeine
O-Dealkylase, Phenacetin
P-450 LM4, Cytochrome
Phenacetin O Dealkylase
Phenacetin O-Dealkylase
Tree Number:
D08.244.453.005.443
D08.244.453.100.750
D08.811.682.690.708.170.010.443
D08.811.682.690.708.170.020.750
D12.776.422.220.453.010.443
D12.776.422.220.453.100.750
Definition
English
:
A
cytochrome
P450 enzyme subtype that has specificity for relatively planar heteroaromatic small molecules, such as
CAFFEINE
and
ACETAMINOPHEN.
Indexing Annotation
English
:
do not confuse with other
cytochrome
P-450 CYP's
Entry Combination - descr/qualif
English
:
Cytochrome P-450 CYP1A2
/
antagonists & inhibitors
use
Cytochrome P-450 CYP1A2 Inhibitors
See Related
English
:
Cytochrome P-450 CYP1A2 Inducers
History Note
English
:
97; was PHENACETIN O-DEALKYLASE (NM) 1976-96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33009
Unique Identifier:
D019388
Occurrence in VHL
:
Similar:
DeCS