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DeCS
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Descriptor English:
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Myasthenia Gravis
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Descriptor Spanish:
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Miastenia Gravis
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Descriptor Portuguese:
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Miastenia Gravis
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Synonyms English:
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Generalized Myasthenia Gravis
Myasthenia Gravis, Generalized
Myasthenia Gravis, Ocular
Ocular Myasthenia Gravis
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Tree Number:
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C10.114.656
C10.668.758.725
C20.111.258.500
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Definition English:
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A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459) |
Indexing Annotation English:
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"myasthenia" unqualified in foreign titles is more often MYASTHENIA GRAVIS than MUSCLE WEAKNESS but check text; congen consider MYASTHENIC SYNDROMES, CONGENITAL or specifics
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See Related English:
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Thymus Hyperplasia
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Allowable Qualifiers English:
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Record Number:
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9349
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Unique Identifier:
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D009157
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Occurrence in VHL:
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Similar:
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DeCS
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