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HLA-C ANTIGENS
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DeCS
Descriptor
English
:
HLA-C Antigens
Descriptor
Spanish
:
Antígenos HLA-C
Descriptor
Portuguese
:
Antígenos HLA-C
Synonyms
English
:
Antigens, HLA C
Antigens, HLA-C
HLA C Antigens
HLA-C
Tree Number:
D12.776.395.550.489.600
D12.776.543.550.439.600
D23.050.301.500.100.600
D23.050.301.500.450.390
D23.050.705.552.100.600
D23.050.705.552.450.390
Definition
English
:
Class I human
histocompatibility
(HLA)
antigens
encoded by a small cluster of structural genes at the C locus on
chromosome 6
. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk
association
with certain
disease
manifestations (e.g.,
spondylarthritis
,
psoriasis
,
multiple myeloma
).
History Note
English
:
89
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23671
Unique Identifier:
D015236
Occurrence in VHL
:
Similar:
DeCS