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FACTOR I
Descriptors Found:
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DeCS
Descriptor
English
:
Fibrinogen
Descriptor
Spanish
:
Fibrinógeno
Descriptor
Portuguese
:
Fibrinogênio
Synonyms
English
:
Blood Coagulation Factor I
Coagulation Factor I
Factor I
Factor I, Coagulation
gamma Fibrinogen
gamma-Fibrinogen
Tree Number:
D12.776.124.050.250
D12.776.124.125.500
D12.776.811.300
D23.119.490
Definition
English
:
Plasma
glycoprotein clotted by
thrombin
, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds.
Fibrinogen
clotting is a sol-gel change involving complex molecular arrangements: whereas
fibrinogen
is cleaved by
thrombin
to form
polypeptides
A and B, the proteolytic action of other
enzymes
yields different
fibrinogen
degradation products.
Indexing Annotation
English
:
a blood coag factor: do not confuse X ref FACTOR I with
COMPLEMENT FACTOR I
Entry Combination - descr/qualif
English
:
Fibrinogen
/
deficiency
use
Afibrinogenemia
See Related
English
:
Coagulants
Hemostatics
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22179
Unique Identifier:
D005340
Occurrence in VHL
:
Similar:
DeCS