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DeCS
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Descriptor English:
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Dianhydrogalactitol
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Descriptor Spanish:
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Dianhidrogalactitol
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Descriptor Portuguese:
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Dianidrogalactitol
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Synonyms English:
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1,2,5,6-Dianhydrogalactitol
1,2-5,6-Dianhydrogalactitol
Dianhydrodulcitol
Diepoxydulcitol
Diepoxygalactitol
NSC 132313
NSC-132313
NSC132313
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Tree Number:
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D02.033.800.400.350
D09.853.400.350
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Definition English:
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One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity. |
Pharmacological Action:
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Antineoplastic Agents, Alkylating
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History Note English:
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91(79); was see under SUGAR ALCOHOLS 1979-90
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Allowable Qualifiers English:
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Record Number:
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3988
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Unique Identifier:
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D003961
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Occurrence in VHL:
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Similar:
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DeCS
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