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ANTAXONE
Descriptors Found:
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DeCS
Descriptor
English
:
Naltrexone
Descriptor
Spanish
:
Naltrexona
Descriptor
Portuguese
:
Naltrexona
Synonyms
English
:
Antaxone
Celupan
EN 1639A
EN-1639A
EN1639A
Nalorex
Naltrexone Hydrochloride
Nemexin
ReVia
Trexan
Tree Number:
D03.132.577.249.706.550
D03.605.497.750.550
D03.633.400.686.750.550
D04.615.723.795.706.550
Definition
English
:
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of
NALOXONE
. It is a narcotic antagonist that is effective orally, longer lasting and more potent than
naloxone
, and has been proposed for the treatment of
heroin
addiction. The FDA has approved
naltrexone
for the treatment of alcohol dependence.
Pharmacological Action:
Alcohol Deterrents
Narcotic Antagonists
History Note
English
:
1986 (1976)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
9463
Unique Identifier:
D009271
Occurrence in VHL
:
Similar:
DeCS