Pesquisa sobre:
MFN=57589
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DeCS
Descritor
Inglês
:
Troglitazone
Descritor
Espanhol
:
Troglitazona
Descritor
Português
:
Troglitazona
Sinônimos
Inglês
:
5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione) - T
CS 045
CS-045
CS045
Prelay
Rezulin
Categoria:
D02.886.675.933.750
D03.383.129.708.933.750
D03.383.663.283.240.612
D03.633.100.150.240.612
Definição
Inglês
:
A chroman and thiazolidinedione derivative that acts as a
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS
(PPAR) agonist. It was formerly used in the treatment of TYPE 2
DIABETES MELLITUS
, but has been withdrawn due to hepatotoxicity.
Ação Farmacológica:
Hypoglycemic Agents
Nota Histórica
Inglês
:
2019 (1988)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Número do Registro:
57589
Identificador Único:
D000077288
Ocorrência na BVS
:
Similar:
DeCS