Search on:
MFN=57082
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
TRPA1 Cation Channel
Descriptor
Spanish
:
Canal Catiónico TRPA1
Descriptor
Portuguese
:
Canal de Cátion TRPA1
Synonyms
English
:
Cation Channel, TRPA1
Channel, TRPA1
Channel, TRPA1 Cation
TRPA1 Channel
Transient Receptor Potential Cation Channel Subfamily A, Member 1
Tree Number:
D12.776.157.530.400.901.250
D12.776.543.585.400.901.250
Definition
English
:
A highly conserved, non-selective TRP cation channel that contains 14-17
ANKYRIN
REPEATS. It functions in cold
sensation
and
NOCICEPTION
of endogenous inflammatory factors and volatile
irritants
. TRPA1 is also activated by
CANNABINOIDS
and may play a role in sound
perception
by hair cells of the inner ear.
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57082
Unique Identifier:
D000074025
Occurrence in VHL
:
Similar:
DeCS