Search on: MFN=54623 
Descriptors Found: 1
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Descriptor English:   B7-H1 Antigen 
Descriptor Spanish:   Antígeno B7-H1 
Descriptor Portuguese:   Antígeno B7-H1 
Synonyms English:   Antigen, B7-H1
Antigen, CD274
Antigens, CD274
B7 H1 Antigen
B7 H1 Immune Costimulatory Protein
B7-H1 Immune Costimulatory Protein
B7H1 Immune Costimulatory Protein
CD274 Antigen
CD274 Antigens
Costimulatory Protein, PD-L1
PD L1 Costimulatory Protein
PD-L1 Costimulatory Protein
Programmed Cell Death 1 Ligand 1
Programmed Cell Death 1 Ligand 1 Protein  
Tree Number:   D12.776.467.150.300
D12.776.543.095.300
D23.050.301.285.400
D23.529.168.300
Definition English:   An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION. 
See Related English:   Immunoglobulin Domains
 
History Note English:   2018 (2007) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54623 
Unique Identifier:   D060890 

Occurrence in VHL: 		 

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DeCS