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SOFOSBUVIR
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DeCS
Descriptor
English
:
Sofosbuvir
Descriptor
Spanish
:
Sofosbuvir
Descriptor
Portuguese
:
Sofosbuvir
Synonyms
English
:
2-((5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy)phenoxyphosphorylamino)propionic acid isopropyl ester
7977, PSI
GS 7977
GS-7977
GS7977
PSI 7977
PSI-7977
PSI7977
Sovaldi
Tree Number:
D03.383.742.686.850.877.500
D13.695.740.850.877.500
D13.695.827.919.877.500
Definition
English
:
A
uridine monophosphate
analog inhibitor of
HEPATITIS C
VIRUS (HCV) polymerase NS5B that is used as an ANTIVIRAL AGENT in the treatment of
CHRONIC HEPATITIS C.
Pharmacological Action:
Antiviral Agents
History Note
English
:
2016 (2010)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
55930
Unique Identifier:
D000069474
Occurrence in VHL
:
Similar:
DeCS