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Descriptor English:   Methysergide 
Descriptor Spanish:   Metisergida 
Descriptor Portuguese:   Metisergida 
Synonyms English:   Deseril
Desril
Dimaleate, Methysergide
Dimethylergometrin
Désernil Sandoz
Désernil-Sandoz
Maleate, Methysergide
Methylmethylergonovine
Methysergide Dimaleate
Methysergide Maleate
Sansert
UML 491
UML-491
UML491  
Tree Number:   D03.132.327.287.689
D03.633.400.439.689
Definition English:   An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome. 
Pharmacological Action:   Serotonin Antagonists
Vasoconstrictor Agents
 
History Note English:   65(63); METHYSERGIDE DERIVATIVES was see under METHYSERGIDE 1975-77; was see under ERGOLINES 1969-74 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   8973 
Unique Identifier:   D008784 

Occurrence in VHL:
 

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DeCS