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PLASMINOGEN
Descriptors Found:
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DeCS
Descriptor
English
:
Plasminogen
Descriptor
Spanish
:
Plasminógeno
Descriptor
Portuguese
:
Plasminogênio
Synonyms
English
:
1-Plasminogen, Glutamic Acid
Glu Plasminogen
Glu-Plasminogen
Glutamic Acid 1 Plasminogen
Glutamic Acid 1-Plasminogen
Glutamyl Plasminogen
Plasminogen, Glutamyl
Profibrinolysin
Tree Number:
D08.622.610
D12.776.124.790.223.580
D12.776.377.715.182.580
Definition
English
:
Precursor of plasmin (
FIBRINOLYSIN
). It is a single-chain beta-globulin of
molecular weight
80-90,000 found mostly in
association
with
fibrinogen
in
plasma
;
plasminogen activators
change it to
fibrinolysin
. It is used in wound debriding and has been investigated as a thrombolytic agent.
Indexing Annotation
English
:
an enzyme precursor & fibrinolytic agent; /antag: do not confuse with
PLASMINOGEN INACTIVATORS
which modulate
PLASMINOGEN ACTIVATORS
, not
PLASMINOGEN
Pharmacological Action:
Fibrinolytic Agents
History Note
English
:
65(63)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
11392
Unique Identifier:
D010958
Occurrence in VHL
:
Similar:
DeCS