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MIRTAZAPINE
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DeCS
Descriptor
English
:
Mirtazapine
Descriptor
Spanish
:
Mirtazapina
Descriptor
Portuguese
:
Mirtazapina
Synonyms
English
:
(N-Methyl-11C)mirtazapine
(S)-Mirtazapine
6 Azamianserin
6-Azamianserin
Esmirtazapine
Norset
ORG 3770
ORG-3770
ORG3770
Org 50081
Remergil
Remeron
Rexer
Zispin
Tree Number:
D03.633.300.240.588
Definition
English
:
A piperazinoazepine tetracyclic compound that enhances the release of
NOREPINEPHRINE
and
SEROTONIN
through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3
serotonin
receptors and is a potent
HISTAMINE
H1 RECEPTOR antagonist. It is used for the treatment of
depression
, and may also be useful for the treatment of
anxiety disorders.
Pharmacological Action:
Antidepressive Agents
Histamine H1 Antagonists
Anti-Anxiety Agents
Adrenergic alpha-2 Receptor Antagonists
Serotonin 5-HT2 Receptor Antagonists
Serotonin 5-HT3 Receptor Antagonists
History Note
English
:
2019 (1982)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57855
Unique Identifier:
D000078785
Occurrence in VHL
:
Similar:
DeCS