Search on: MELPHALAN 
Descriptors Found: 1
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Descriptor English:   Melphalan 
Descriptor Spanish:   Melfalán 
Descriptor Portuguese:   Melfalan 
Synonyms English:   4-(Bis(2-chloroethyl)amino)phenylalanine
Alkeran
L-PAM
Medphalan
Merphalan
Mustard, Phenylalanine
Phenylalanine Mustard
Sarcolysine
Sarkolysin  
Tree Number:   D02.455.526.728.650.594
D12.125.072.050.685.500
Definition English:   An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen. 
Pharmacological Action:   Antineoplastic Agents, Alkylating
Myeloablative Agonists
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   8727 
Unique Identifier:   D008558 

Occurrence in VHL:
 

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