Search on: LOPINAVIR 
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Descriptor English:   Lopinavir 
Descriptor Spanish:   Lopinavir 
Descriptor Portuguese:   Lopinavir 
Synonyms English:   A 157378.0
A-157378.0
A157378.0
ABT 378
ABT-378
ABT378
N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide  
Tree Number:   D03.383.742.698.553
Definition English:   An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A. 
Pharmacological Action:   HIV Protease Inhibitors
Cytochrome P-450 CYP3A Inhibitors
 
History Note English:   2012 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   54552 
Unique Identifier:   D061466 

Occurrence in VHL:
 

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