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DANCOR
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DeCS
Descriptor
English
:
Nicorandil
Descriptor
Spanish
:
Nicorandil
Descriptor
Portuguese
:
Nicorandil
Synonyms
English
:
2 Nicotinamidethyl Nitrate
2 Nicotinamidoethyl Nitrate
2-Nicotinamidethyl Nitrate
2-Nicotinamidoethyl Nitrate
Adancor
Dancor
Ikorel
Nitrate, 2-Nicotinamidethyl
Nitrate, 2-Nicotinamidoethyl
SG 75
SG-75
SG75
Tree Number:
D02.583.575
D03.066.515.530.498
D03.383.725.547.530.498
Definition
English
:
A derivative of the
NIACINAMIDE
that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of
arterioles
and large coronary
arteries
. Its nitrate-like properties produce venous
vasodilation
through stimulation of
guanylate cyclase.
Pharmacological Action:
Anti-Arrhythmia Agents
Antihypertensive Agents
Vasodilator Agents
Vitamin B Complex
History Note
English
:
99; use NICORANDIL (NM) 1978-98
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
33810
Unique Identifier:
D020108
Occurrence in VHL
:
Similar:
DeCS