Search on: ABATACEPT 
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Descriptor English:   Abatacept 
Descriptor Spanish:   Abatacept 
Descriptor Portuguese:   Abatacepte 
Synonyms English:   BMS 188667
BMS 224818
BMS-188667
BMS-224818
BMS188667
BMS224818
Belatacept
CTLA-4-Ig
CTLA4 Ig Immunoconjugate
CTLA4-Fc
CTLA4-Ig
CTLA4-Ig Immunoconjugate
Cytotoxic T Lymphocyte Associated Antigen 4 Immunoglobulin
Cytotoxic T Lymphocyte-Associated Antigen 4-Immunoglobulin
Immunoconjugate, CTLA4-Ig
LEA29Y
Nulojix
Orencia  
Tree Number:   D12.776.124.790.651.114.580.225
D12.776.377.715.548.114.580.225
Definition English:   A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS. 
Pharmacological Action:   Immunosuppressive Agents
Antirheumatic Agents
 
See Related English:   CTLA-4 Antigen
 
History Note English:   2016 (2002) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55984 
Unique Identifier:   D000069594 

Occurrence in VHL:
 

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