Search on: A272 
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Descriptor English:   Rutamycin 
Descriptor Spanish:   Rutamicina 
Descriptor Portuguese:   Rutamicina 
Synonyms English:   A 272
A-272
A272
Oligomycin D
RR 32705
RR-32705
RR32705  
Tree Number:   D02.540.505.620.750
Definition English:   A macrolide antibiotic of the oligomycin group, obtained from Streptomyces rutgersensis. It is used in cytochemistry as a tool to inhibit various ATPases and to uncouple oxidative phosphorylation from electron transport and also clinically as an antifungal agent. 
Pharmacological Action:   Anti-Bacterial Agents
Antifungal Agents
Enzyme Inhibitors
Uncoupling Agents
 
History Note English:   91(75); was see under OLIGOMYCINS 1982-90; was see under ANTIBIOTICS, ANTIFUNGAL 1975-81 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   12800 
Unique Identifier:   D012427 

Occurrence in VHL:
 

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