Search on: 6-PHOSPHOFRUCTOKINASE 
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Descriptor English:   Phosphofructokinase-1 
Descriptor Spanish:   Fosfofructoquinasa-1 
Descriptor Portuguese:   Fosfofrutoquinase-1 
Synonyms English:   6 Phosphofructokinase
6-Phosphofructo-1-kinase
6-Phosphofructokinase
Fructose-6-P 1-Kinase
Fructose-6-phosphate 1-Phosphotransferase
Phosphofructokinase 1  
Tree Number:   D08.811.913.696.620.225.850.500
Definition English:   An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues. 
Indexing Annotation English:   GEN or unspecified; prefer specifics
See Related English:   Glycogen Storage Disease Type VII
Phosphofructokinase-2
 
History Note English:   2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   30875 
Unique Identifier:   D010732 

Occurrence in VHL:
 

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