Search on: 5-LIPOXYGENASE 
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Descriptor English:   Arachidonate 5-Lipoxygenase 
Descriptor Spanish:   Araquidonato 5-Lipooxigenasa 
Descriptor Portuguese:   Araquidonato 5-Lipoxigenase 
Synonyms English:   5 Lipoxygenase
5-Lipoxygenase
5-Lipoxygenase, Arachidonate
5-Lipoxygenase, Arachidonic Acid
Arachidonate 5 Lipoxygenase
Arachidonic Acid 5 Lipoxygenase
Arachidonic Acid 5-Lipoxygenase
LTA4 Synthase
Leukotriene A Synthase
Leukotriene A4 Synthase
Leukotriene A4 Synthetase
Synthase, LTA4
Synthase, Leukotriene A
Synthase, Leukotriene A4
Synthetase, Leukotriene A4  
Tree Number:   D08.811.682.690.416.583.500.055
D12.776.556.579.374.568.500.020
Definition English:   An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes. 
Entry Combination - descr/qualif English:   Arachidonate 5-Lipoxygenase/antagonists & inhibitors use Lipoxygenase Inhibitors
 
History Note English:   91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   19074 
Unique Identifier:   D001094 

Occurrence in VHL:
 

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