Search on: 4-NITROPHENOL-2-HYDROXYLASE 
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Descriptor English:   Cytochrome P-450 CYP2E1 
Descriptor Spanish:   Citocromo P-450 CYP2E1 
Descriptor Portuguese:   Citocromo P-450 CYP2E1 
Synonyms English:   4 Nitrophenol 2 Hydroxylase
4-Nitrophenol-2-Hydroxylase
CYP 2E1
CYP IIE1
CYP2E1
CYPIIE1
Cytochrome P 450 CYP2E1
Cytochrome P 450 IIE1
Cytochrome P 450 J
Cytochrome P-450 (ALC)
Cytochrome P-450 IIE1
Cytochrome P-450-J
Cytochrome P450 2E1
Dimethylnitrosamine N Demethylase
Dimethylnitrosamine N-Demethylase
N Nitrosodimethylamine Demethylase
N-Nitrosodimethylamine Demethylase  
Tree Number:   D08.244.453.491.375
D08.811.682.662.582.338
D08.811.682.690.708.170.450.375
D12.776.422.220.453.491.375
Definition English:   An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse. 
Indexing Annotation English:   do not confuse with other cytochrome P-450 CYP's
Entry Combination - descr/qualif English:   Cytochrome P-450 CYP2E1/antagonists & inhibitors use Cytochrome P-450 CYP2E1 Inhibitors
 
History Note English:   97; was DIMETHYLNITROSAMIME N-DEMETHYLASE (NM) 1972-96 & was 4-NITROPHENOL-2-HYDROXYLASE (NM) 1984-96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   33012 
Unique Identifier:   D019392 

Occurrence in VHL:
 

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