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DeCS
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Descriptor English:
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Steroid 17-alpha-Hydroxylase
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Descriptor Spanish:
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Esteroide 17-alfa-Hidroxilasa
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Descriptor Portuguese:
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Esteroide 17-alfa-Hidroxilase
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Synonyms English:
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17 alpha Hydroxylase
17 alpha Hydroxylase Cytochrome P 450
17 alpha Hydroxyprogesterone Aldolase
17 alpha-Hydroxylase
17 alpha-Hydroxylase Cytochrome P-450
17 alpha-Hydroxylase, Steroid
17 alpha-Hydroxyprogesterone Aldolase
17 alpha-Monooxygenase, Steroid
17,20 Desmolase
17,20 Lyase
17,20-Desmolase
17,20-Lyase
17-Hydroxylase, Steroid
17-Monooxygenase, Steroid
17-alpha-Hydroxylase, Steroid
Aldolase, 17 alpha-Hydroxyprogesterone
Aldolase, Hydroxyprogesterone
CYP17
Cytochrome P-450(17 alpha)
Cytochrome P-450(17-alpha)
Cytochrome P450(17 alpha)
Hydroxyprogesterone Aldolase
P450(c17)
Steroid 17 Hydroxylase
Steroid 17 Monooxygenase
Steroid 17 alpha Hydroxylase
Steroid 17 alpha Monooxygenase
Steroid 17 alpha-Hydroxylase
Steroid 17 alpha-Monooxygenase
Steroid 17-Hydroxylase
Steroid 17-Monooxygenase
Steroid-17-Hydroxylase
alpha-Hydroxyprogesterone Aldolase, 17
alpha-Monooxygenase, Steroid 17
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Tree Number:
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D08.244.453.487.500
D08.244.453.915.748
D08.811.682.690.708.170.444.500
D08.811.682.690.708.170.915.748
D12.776.422.220.453.487.500
D12.776.422.220.453.915.748
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Definition English:
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A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation. |
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Entry Combination - descr/qualif English:
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Steroid 17-alpha-Hydroxylase/deficiency use Adrenal Hyperplasia, Congenital
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See Related English:
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Adrenal Hyperplasia, Congenital
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History Note English:
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2003 (1978)
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Allowable Qualifiers English:
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Record Number:
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23464
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Unique Identifier:
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D013254
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Occurrence in VHL:
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Similar:
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DeCS
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