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DeCS
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Descriptor Inglés:
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Promyelocytic Leukemia Zinc Finger Protein
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Descriptor Español:
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Proteína de la Leucemia Promielocítica con Dedos de Zinc
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Descriptor Portugués:
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Proteína com Dedos de Zinco da Leucemia Promielocítica
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Sinónimos Inglés:
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PLZF Protein
Promyelocytic Leukaemia Zinc Finger Protein
ZBTB16 Protein
Zinc Finger and BTB Domain Containing 16 Protein
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Categoría:
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D12.776.260.522.625
D12.776.930.375.625
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Definición Inglés:
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A Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA. |
Nota Histórica Inglés:
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2018
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Calificadores Permitidos Inglés:
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Número del Registro:
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57115
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Identificador Único:
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D000075722
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Ocurrencia en la BVS:
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Similar:
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DeCS
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