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DeCS
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Descriptor Inglés:
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KRIT1 Protein
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Descriptor Español:
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Proteína KRIT1
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Descriptor Portugués:
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Proteína KRIT1
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Sinónimos Inglés:
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Cerebral Cavernous Malformations 1 Protein
Krev Interaction Trapped Protein 1
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Categoría:
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D12.776.220.600.450.458
D12.776.624.664.700.119
D12.776.631.560.465
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Definición Inglés:
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A microtubule-associated protein consisting of four ANKYRIN REPEATS and a C-terminal FERM DOMAIN. It links the CYTOSKELETON to CELL JUNCTIONS via integrin cytoplasmic domain-associated protein-1 and plays an important role in regulating cell proliferation and integrity of endothelial cell junctions. It is also involved in REACTIVE OXYGEN SPECIES metabolism. Mutations in the KRIT1 gene are associated with type I CEREBRAL CAVERNOUS MALFORMATIONS. |
Nota Histórica Inglés:
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2018
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Calificadores Permitidos Inglés:
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Número del Registro:
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57104
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Identificador Único:
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D000075927
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Ocurrencia en la BVS:
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Similar:
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DeCS
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