1 / 1
|
DeCS
|
|
|
Descriptor Inglés:
|
|
Lysine Acetyltransferase 5
|
Descriptor Español:
|
|
Lisina Acetiltransferasa 5
|
Descriptor Portugués:
|
|
Lisina Acetiltransferase 5
|
Sinónimos Inglés:
|
|
HIV 1 Tat Interactive Protein Tip60
HIV-1-Tat Interactive Protein Tip60
HTATIP
KAT5 (TIP60) Protein
|
Categoría:
|
|
D08.811.913.050.134.415.500.062
|
Definición Inglés:
|
|
A catalytic subunit of the NuA4 histone acetyltransferase complex that functions in transcriptional activation of genes by acetylation of nucleosomal HISTONES H4 and H2A, altering nucleosome-DNA interactions and interaction of the modified histones with other activating transcription factors. It may control gene expression changes associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest; CELL AGING; APOPTOSIS; and DNA REPAIR. It is polyubiquitinated and degraded during HIV-1 infection through its interaction with the viral TAT PROTEIN. |
Nota Histórica Inglés:
|
|
2018
|
Calificadores Permitidos Inglés:
|
|
|
Número del Registro:
|
|
57027
|
Identificador Único:
|
|
D000074443
|
Ocurrencia en la BVS:
|
|
|
Similar:
|
|
DeCS
|