Search on: METALLOPROTEASES 
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Descriptor English:   Metalloproteases 
Descriptor Spanish:   Metaloproteasas 
Descriptor Portuguese:   Metaloproteases 
Synonyms English:   Metallopeptidases
Metalloproteinases  
Tree Number:   D08.811.277.656.675
Definition English:   Proteases which use a metal, normally ZINC, in the catalytic mechanism. This group of enzymes is inactivated by metal CHELATORS. 
Indexing Annotation English:   GEN; prefer specifics
History Note English:   2004; use METALLOENDOPEPTIDASES 1988-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38178 
Unique Identifier:   D045726 

Occurrence in VHL:
 

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