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ANTIBODIES, BLOCKING
Descriptors Found:
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DeCS
Descriptor
English
:
Antibodies, Blocking
Descriptor
Spanish
:
Anticuerpos Bloqueadores
Descriptor
Portuguese
:
Anticorpos Bloqueadores
Synonyms
English
:
Antibodies, Enhancing
Blocking Antibodies
Enhancing Antibodies
Tree Number:
D12.776.124.486.485.114.143
D12.776.124.790.651.114.143
D12.776.377.715.548.114.143
Definition
English
:
Antibodies
that inhibit the reaction between
ANTIGEN
and other
antibodies
or sensitized
T-LYMPHOCYTES
(e.g.,
antibodies
of the
IMMUNOGLOBULIN G
class that compete with IGE
antibodies
for
antigen
, thereby blocking an allergic response). Blocking
antibodies
that bind tumors and prevent destruction of tumor cells by CYTOTOXIC
T-LYMPHOCYTES
have also been called enhancing
antibodies
. (Rosen et al.,
Dictionary
of Immunology, 1989)
Indexing Annotation
English
:
antibodies
inhibiting reaction between
antigen
and other
antibodies
or sensitized
T-lymphocytes
: not for any antibody reaction to an
antigen
( =
ANTIBODIES
or specific antibody); do not coordinate with
ANTIBODY FORMATION
for /biosyn
Pharmacological Action:
Immunologic Factors
History Note
English
:
96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
32855
Unique Identifier:
D019138
Occurrence in VHL
:
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