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DeCS
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Descriptor English:
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Aldo-Keto Reductases
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Descriptor Spanish:
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Aldo-Ceto Reductasas
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Descriptor Portuguese:
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Aldo-Ceto Redutases
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Synonyms English:
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Aldo Keto Reductase
Aldo Keto Reductase Family
Aldo Keto Reductase Superfamily
Aldo Keto Reductases
Aldo-Keto Reductase
Aldo-Keto Reductase Family
Aldo-Keto Reductase Superfamily
Reductase, Aldo-Keto
Reductases, Aldo-Keto
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Tree Number:
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D08.811.682.047.150.700.156
D08.811.682.047.820.284
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Definition English:
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A family of NADPH-dependent oxidoreductases that reduce carbonyl substrates including sugar-aldehydes, KETOSTEROIDS; keto-prostaglandins, and QUINONES. They are monomers of approximately 37 KDa and are characterized by a parallel beta-8 (BETA SHEET)-alpha 8 (ALPHA HELICES)-barrel structure that contains the NADP binding site. This conformation favors aromatic and apolar substrates. |
History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57015
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Unique Identifier:
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D000074408
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Occurrence in VHL:
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Similar:
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DeCS
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